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Updated: Mar 18, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Using extracorporeal membrane oxygenation support preoperatively and postoperatively as a successful bridge to
Samuel Jacob1, Mitesh J Patel1, Brian Lima1
1Department of Cardiac and Thoracic Surgery (Jacob, Patel, Lima, Malyala, Chamogeorgakis, MacHannaford, Gonzalez-Stawinski, Rafael) and the Annette C. and Harold C. Simmons Transplant Institute (Lima, Felius, Chamogeorgakis, Gonzalez-Stawinski), Baylor University Medical Center at Dallas.
Abstract:
Rupture of the ventricular septum during acute myocardial infarction usually occurs within the first week. The event is usually followed by low cardiac output, heart failure, and multiorgan failure. Despite the many advances in the nonoperative treatment of heart failure and cardiogenic shock, including the intra-aortic balloon pump and a multitude of new inotropic agents and vasodilators, these do not supplant the need for operative intervention in these critically ill patients. This article describes the successful use of extracorporeal membrane oxygenation support as a bridge to recovery postoperatively in a patient with a large infarct-produced ventricular septal defect.
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