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Measles Outbreak among Previously Immunized Adult Healthcare Workers, China, 2015

Zhengyi Zhang1, Yuan Zhao1, Lili Yang1

  • 1Department of General Medicine, Lanzhou University Second Hospital, Gansu 730030, China.

The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale
|July 2, 2016
PubMed

Insights

A measles outbreak occurred in a hospital, primarily affecting vaccinated healthcare workers. This highlights the need for strict adherence to two-dose measles vaccination and prompt recognition of symptoms in medical staff to prevent nosocomial spread.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Measles virus (Morbillivirus, Paramyxoviridae) infection is a global health concern.
  • Vaccination is key to measles control, yet outbreaks persist, especially in developing nations.
  • Healthcare settings can be vulnerable to measles transmission, posing risks to staff and patients.

Purpose of the Study:

  • To report and analyze a measles outbreak within a hospital setting.
  • To identify contributing factors to the outbreak's spread among healthcare workers.
  • To emphasize the importance of vaccination and early detection in preventing nosocomial measles.

Main Methods:

  • Retrospective analysis of a measles outbreak involving 60 patients.
  • Clinical data collection and laboratory confirmation (IgM antibodies, viral RNA).
  • Review of hospital protocols and initial response to suspected cases.

Main Results:

  • 50 out of 60 (83.3%) measles patients were healthcare workers.
  • 73.3% of infected individuals had prior measles immunization.
  • Delayed recognition of symptoms and lack of isolation contributed to the hospital-wide outbreak.

Conclusions:

  • The study underscores the critical need for a two-dose measles vaccination schedule for all individuals, including healthcare professionals.
  • Vigilant monitoring of healthcare staff presenting with fever and rash is essential to prevent nosocomial measles transmission.
  • Improved diagnostic and isolation protocols are necessary to contain outbreaks in hospital environments.

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