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[The probability of survival in children with heart defects not treated surgically]
Insights
Survival rates for children with congenital heart disease before cardiac surgery were estimated. Most infants survived the first week, but long-term survival was limited, with specific conditions offering better or worse prognoses.
Area of Science:
- Pediatric Cardiology
- Medical History
- Public Health
Context:
- Historical data from Bohemia prior to cardiac surgery.
- Utilized necropsy records and child population heart disease incidence.
- Focused on congenital heart disease (CHD) in liveborn infants.
Purpose:
- To calculate probable survival rates for children with CHD.
- To identify prognostic factors for different CHD types.
- To establish a baseline for survival before surgical intervention.
Summary:
- 90% of infants with CHD survived the first week, 86% the first month, 74% six months, 71% the first year, and 67% reached 15 years.
- Pulmonary stenosis and ventricular septal defects showed favorable prognoses.
- Hypoplastic left heart syndrome, double outlet right ventricle, and others had the most adverse prognoses.
Impact:
- Provides historical survival data for CHD before surgical advancements.
- Highlights the significant impact of specific congenital heart defects on long-term outcomes.
- Establishes a benchmark for evaluating the effectiveness of future cardiac surgeries.
Abstract:
Data on the age at death of children with congenital heart disease recorded 27 years before the introduction of cardiacsurgery on a territory where all deceased children were subjected to necropsy and data on the incidence of heart disease in the child population in Bohemia were used to calculate probable survival. Of liveborn infants with heart disease 90% surviev the first week, 86% the first month, 74% six month, 71% the first year and 67% 15 years. Pulmonary stenosis and a ventricular septal defect have the most favourable prognosis. The syndrome of a hypoplastic left heart, double outlow right ventricle, total anomalous pulmonary venous return, arterial truncus and pulmonary atresia have the most adverse prognosis.