Related Experiment Video
Updated: Mar 18, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Perioperative Management of Severe Hypertension during Laparoscopic Surgery for Pheochromocytoma
Mehmet Ali Erdoğan1, Muharrem Uçar1, Ahmet Selim Özkan1
1Department of Anaesthesiology and Reanimation, İnönü University School of Medicine, Turgut Özal Medical Center, Malatya, Turkey.
Insights
This study details managing severe hypertension in phaeochromocytoma patients during laparoscopic surgery. It highlights a combined approach using alpha-adrenergic blockade, beta-adrenergic blockade, sodium nitroprusside, and remifentanil for effective control.
Area of Science:
- Anesthesiology
- Endocrinology
- Cardiovascular Medicine
Background:
- Phaeochromocytoma is a rare tumor secreting catecholamines, leading to severe hypertension and cardiovascular risks.
- Anesthetic management is critical due to potential catecholamine surges during surgery.
- Laparoscopic surgery for phaeochromocytoma presents unique anesthetic challenges.
Observation:
- A patient undergoing laparoscopic phaeochromocytoma surgery experienced severe, persistent hypertension.
- Catecholamine release during surgical manipulation posed a significant risk.
Findings:
- Preoperative preparation included alpha-adrenergic blockade and beta-adrenergic blockade.
- Intraoperative management utilized a combination of sodium nitroprusside and remifentanil.
- This multi-agent strategy effectively controlled the hypertensive crisis.
Implications:
- This case demonstrates a successful anesthetic strategy for managing hypertensive crises in phaeochromocytoma surgery.
- Effective preoperative and intraoperative control is crucial for patient safety.
- The combined blockade and infusion approach offers a viable option for complex cases.
Abstract:
Phaeochromocytoma is a catecholamine-secreting vascular tumour that is derived from chromaffin cell. Lethal cardiovascular complications, such as serious hypertension, myocardial infarction and aortic dissection, may occur because of uncontrolled catecholamine release. Each stage of anaesthesia management has vital importance because of this destructive catecholamine secretion that may occur during induction, perioperative stage and surgical manipulation. In this study, we report regarding the preoperative preparation and severe, persistent hypertension attack management with a combination of α-adrenergic blockade, β-adrenergic blockade, sodium nitroprusside and remifentanil in a patient who underwent laparoscopic surgery for phaeochromocytoma.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Aneurysm IV: Nursing Management
Cardiopulmonary Resuscitation IV: Pharmacological Management
Heart Failure V: Medical Management
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Peripheral Artery Disease V: Postoperative Nursing Management

