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Related Concept Videos

Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Imaging Studies III: Computed Tomography01:27

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Radiological Investigation I: X-ray and CT01:30

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Imaging Studies for Cardiovascular System IV: CMRI01:21

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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Related Experiment Video

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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
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Alternatives to GBCA: Are We There Yet?

Jeffrey R Wesolowski1, Andrew Kaiser

  • 1University of Michigan Health System, Ann Arbor, MI.

Topics in Magnetic Resonance Imaging : TMRI
|July 2, 2016
PubMed
Summary

Gadolinium contrast agents for MRI have risks. This review covers iron- and manganese-based alternatives, discussing their use in contrast-enhanced magnetic resonance imaging (MRI) examinations.

Area of Science:

  • Medical Imaging
  • Radiology
  • Materials Science

Background:

  • Gadolinium-based contrast agents (GBCAs) are standard for MRI.
  • Concerns exist regarding GBCAs' side effects, including nephrogenic systemic fibrosis.
  • Alternative contrast agents are needed to mitigate these risks.

Purpose of the Study:

  • To review alternatives to gadolinium contrast agents for MRI.
  • To discuss iron- and manganese-based contrast agents.
  • To evaluate their current clinical applications in contrast-enhanced MRI.

Main Methods:

  • Literature review of gadolinium alternatives.
  • Analysis of iron- and manganese-based contrast agents.
  • Examination of clinical usage data for enhanced MRI.

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Main Results:

  • Iron- and manganese-based agents show promise as MRI contrast agents.
  • These alternatives offer different enhancement properties and safety profiles.
  • Current clinical adoption varies, with ongoing research into broader applications.

Conclusions:

  • Iron- and manganese-based agents represent viable alternatives to gadolinium for MRI.
  • Further research and clinical trials are needed to expand their use.
  • These agents may offer improved safety and efficacy in specific patient populations.