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Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes in Pediatric Intensive Care. A Multicenter Study
Punkaj Gupta1,2, Mallikarjuna Rettiganti3,2, Tom B Rice4,5
11 Division of Pediatric Cardiology, and.
Insights
Twenty-four-hour in-house attending critical care physician coverage in pediatric intensive care units (PICUs) is linked to better patient survival and fewer adverse events. This finding supports the importance of continuous intensivist presence for critically ill children.
Area of Science:
- Pediatric Critical Care Medicine
- Healthcare Quality Improvement
- Intensivist Staffing Models
Background:
- Continuous in-house attending physician coverage (24/7) in pediatric intensive care units (PICUs) is hypothesized to improve outcomes for critically ill children.
- Previous research suggests a potential benefit, but robust evidence is needed to confirm this association.
Purpose of the Study:
- To investigate the association between 24/7 in-house attending critical care physician coverage and patient outcomes in a large cohort of critically ill children.
- To determine if continuous intensivist presence impacts mortality, cardiac arrest rates, and length of stay in the PICU.
Main Methods:
- A retrospective analysis of the Virtual Pediatric Systems Database (2009-2014) included over 455,000 patients from 125 hospitals.
- Generalized linear mixed effects multivariable regression models were used for the main analysis.
- Multiple sensitivity analyses were conducted to ensure the robustness of the findings.
Main Results:
- Hospitals with 24/7 intensivist coverage showed significantly lower intensive care unit (ICU) mortality (OR, 0.52; P=0.002).
- 24/7 coverage was associated with reduced cardiac arrest incidence (OR, 0.73; P=0.04) and lower post-arrest mortality (OR, 0.56; P=0.02).
- Patients in 24/7 ICUs experienced shorter ICU stays and reduced mechanical ventilation duration.
Conclusions:
- This large observational study demonstrates that 24/7 intensivist presence in PICUs is associated with improved survival and reduced adverse events in critically ill children.
- The findings suggest that continuous intensivist staffing is a valuable model for enhancing care quality and patient outcomes.
- While generally robust, some sensitivity analyses indicated minor ambiguities, warranting further investigation.
Rationale:
The around-the-clock presence of an in-house attending critical care physician (24/7 coverage) is purported to be associated with improved outcomes among high-risk children with critical illness.
Objectives:
To evaluate the association of 24/7 in-house coverage with outcomes in children with critical illness.
Methods:
Patients younger than 18 years of age in the Virtual Pediatric Systems Database (2009-2014) were included. The main analysis was performed using generalized linear mixed effects multivariable regression models. In addition, multiple sensitivity analyses were performed to test the robustness of our findings.
Measurements And Main Results:
A total of 455,607 patients from 125 hospitals were included (24/7 group: 266,319 patients; no 24/7 group: 189,288 patients). After adjusting for patient and center characteristics, the 24/7 group was associated with lower mortality in the intensive care unit (ICU) (24/7 vs. no 24/7; odds ratio [OR], 0.52; 95% confidence interval [CI], 0.33-0.80; P = 0.002), a lower incidence of cardiac arrest (OR, 0.73; 95% CI, 0.54-0.99; P = 0.04), lower mortality after cardiac arrest (OR, 0.56; 95% CI, 0.340-0.93; P = 0.02), a shorter ICU stay (mean difference, -0.51 d; 95% CI, -0.93 to -0.09), and shorter duration of mechanical ventilation (mean difference, -0.68 d; 95% CI, -1.23 to -0.14).
Conclusions:
In this large observational study, we demonstrated that pediatric critical care provided in the ICUs staffed with a 24/7 intensivist presence is associated with improved overall patient survival and survival after cardiac arrest compared with patients treated in ICUs staffed with discretionary attending coverage. However, results from a few sensitivity analyses leave some ambiguity in these results.
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