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Updated: Mar 18, 2026
A Murine Tail Lymphedema Model
Published on: February 10, 2021
Pediatric lymphedema caused by diffuse cervical lymphadenopathy: A case report and review of the literature
Sarah A Gitomer1, Carla M Giannoni2, Karina T Cañadas2
1Baylor College of Medicine, Bobby R. Alford Department of Otolaryngology, Houston, TX, USA.
Insights
Pediatric head and neck lymphedema, though rare, can occur in children due to conditions like Kawasaki disease. Prompt recognition and treatment are crucial for managing this condition and preventing severe complications.
Area of Science:
- Pediatric Otolaryngology
- Pediatric Lymphology
- Pediatric Rheumatology
Background:
- Pediatric head and neck lymphedema is an exceptionally rare condition with no prior documented cases in children.
- Kawasaki disease can lead to significant lymphadenopathy, potentially causing secondary complications.
Observation:
- A severe, diffuse case of pediatric head and neck lymphedema was observed.
- The lymphedema was attributed to lymphadenopathy secondary to Kawasaki disease, compressing the internal jugular veins.
Findings:
- Treatment with corticosteroids and intravenous immunoglobulin led to the resolution of lymphadenopathy.
- The patient's facial edema gradually subsided following the intervention.
Implications:
- This case underscores the necessity for pediatric otolaryngologists to consider lymphedema in the differential diagnosis of pediatric facial swelling.
- Early identification and management are vital to mitigate potential complications such as airway obstruction and visual impairment.
Abstract:
Pediatric head and neck lymphedema is rare and there have not been any reported cases in children. Here we discuss severe, diffuse head and neck lymphedema in a child caused by compression of the internal jugular veins by lymphadenopathy from Kawasaki's disease. With steroid and intravenous immunoglobulin treatment, the lymphadenopathy improved and facial edema slowly resolved. In review of the literature, complications of head and neck lymphedema including airway obstruction and blindness are discussed. This case highlights the importance of the pediatric otolaryngologist considering lymphedema as a cause for facial swelling and monitoring for complications of lymphedema.
