Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intracellular Signaling Cascades01:24

Intracellular Signaling Cascades

54.9K
Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...
54.9K
Intracellular Signaling Cascades01:24

Intracellular Signaling Cascades

37.2K
37.2K
Amplifying Signals via Enzymatic Cascade01:22

Amplifying Signals via Enzymatic Cascade

19.0K
When a ligand binds to a cell-surface receptor, the receptor's intracellular domain changes shape, which may either activate its enzyme function or allow its binding to other molecules. The initial signal is amplified by most signal transduction pathways. This means that a single ligand molecule can activate multiple molecules of a downstream target. Proteins that relay a signal are most commonly phosphorylated at one or more sites, activating or inactivating the protein. Kinases catalyze...
19.0K
Ecological Succession02:17

Ecological Succession

22.0K
Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...
22.0K
Speciation Rates01:07

Speciation Rates

23.4K
Overview
23.4K
Threats to Biodiversity01:50

Threats to Biodiversity

27.7K
There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
27.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The potential of the programmable gaming mouse in diagnostic radiology residency.

Current problems in diagnostic radiology·2026
Same author

A CFIR-guided qualitative study of digital health engagement among Black adults with type 2 diabetes.

NPJ digital medicine·2025
Same author

The role of place types on social relationships and satisfaction as influenced by COVID and disabilities.

Frontiers in rehabilitation sciences·2025
Same author

Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Supervised and unsupervised rehabilitation of visual field defect: cohort investigation of eye movement training at a clinical setting and at home.

Experimental brain research·2025
Same author

Structural Imaging Measures of Cortical and Basal Ganglia Morphology in Insomnia.

Journal of sleep research·2025

Related Experiment Video

Updated: Mar 18, 2026

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading
10:54

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading

Published on: May 22, 2021

6.2K

From neurons to epidemics: How trophic coherence affects spreading processes.

Janis Klaise1, Samuel Johnson1

  • 1Centre for Complexity Science, University of Warwick, Coventry CV4 7AL, United Kingdom.

Chaos (Woodbury, N.Y.)
|July 3, 2016
PubMed
Summary

Trophic coherence in complex networks influences how activity, like epidemics or rumors, spreads. Higher coherence can prevent widespread outbreaks, while lower coherence may lead to sustained activity across the network.

More Related Videos

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter
10:20

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter

Published on: March 12, 2013

14.1K
Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy
05:50

Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy

Published on: November 1, 2021

2.9K

Related Experiment Videos

Last Updated: Mar 18, 2026

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading
10:54

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading

Published on: May 22, 2021

6.2K
Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter
10:20

Linking Predation Risk, Herbivore Physiological Stress and Microbial Decomposition of Plant Litter

Published on: March 12, 2013

14.1K
Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy
05:50

Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy

Published on: November 1, 2021

2.9K

Area of Science:

  • Complex Systems Science
  • Network Theory
  • Mathematical Biology

Background:

  • Trophic coherence quantifies hierarchical organization in directed networks.
  • It impacts network dynamics, stability, and structural properties.
  • Trophic structures are found across diverse systems like neural, ecological, and social networks.

Purpose of the Study:

  • To investigate the role of trophic coherence in modulating spreading processes within complex networks.
  • To demonstrate that different dynamical models exhibit similar responses to varying trophic coherence.
  • To introduce a network assembly model for generating tunable trophic coherence.

Main Methods:

  • Adaptation of a susceptible-infected-susceptible (SIS) epidemic model with complex contagion.
  • Utilizing an Amari-Hopfield neural network model.
  • Development of a network assembly model to control trophic coherence levels.

Main Results:

  • Spreading processes in both epidemic and neural network models are significantly modulated by network trophic coherence.
  • Trophic coherence can qualitatively alter spreading behavior, determining percolation and persistence of activity.
  • The network assembly model successfully generated structures with tunable trophic coherence, ranging from stratified to random graphs.

Conclusions:

  • Trophic coherence is a critical factor influencing the dynamics of spreading phenomena in complex networks.
  • Understanding trophic coherence can provide insights into the behavior of epidemics, rumors, and neuronal avalanches.
  • The findings highlight the universal impact of network hierarchy on dynamical processes across various scientific domains.