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Updated: Mar 18, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
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Primary adrenal leiomyosarcoma with lymph node metastasis: a case report.

Tomoya Onishi1, Yutaka Yanagihara2, Tadahiko Kikugawa1

  • 1Department of Urology, Ehime University Graduate School of Medicine, 454 Shitsukawa, Toon, Ehime, 791-0295, Japan.

World Journal of Surgical Oncology
|July 3, 2016
PubMed
Summary

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Primary adrenal leiomyosarcoma is a rare tumor. Aggressive surgical resection, including vascular reconstruction, may improve survival for patients with this rare adrenal cancer.

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Leiomyosarcomas are malignant tumors originating from smooth muscle cells.
  • Primary adrenal leiomyosarcoma is an exceptionally rare mesenchymal tumor with a typically poor prognosis and delayed diagnosis.

Observation:

  • A 34-year-old male presented with right hypochondriac pain.
  • Computed tomography revealed a 5.2 cm solid mass in the right adrenal gland with suspected inferior vena cava (IVC) invasion.
  • The patient underwent right adrenalectomy and lymphadenectomy.

Findings:

  • Microscopic examination confirmed primary adrenal leiomyosarcoma with lymph node metastasis.
  • The patient remained recurrence-free at 10 months post-surgery without adjuvant therapy.

Implications:

Keywords:
AdrenalectomyIVC reconstructionPrimary adrenal leiomyosarcoma

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  • This case highlights the rarity of primary adrenal leiomyosarcoma.
  • Aggressive surgical management, potentially including vascular reconstruction, may be crucial for improving survival outcomes in these rare adrenal tumors.