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Updated: Mar 18, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Biological therapy and neurological manifestations. What do we know?
Beatriz Tejera-Segura1, Iván Ferraz-Amaro1
1Servicio de Reumatología, Hospital Universitario de Canarias, Tenerife, España.
Abstract:
Biological therapy has changed the course of inflammatory rheumatic diseases. The safety is well documented in national and international studies. Neurological manifestations are uncommon and it is difficult to establish a clear causal relationship. The neurological signs and symptoms that may appear are multiple and sometimes mimic demyelinating neurological diseases and/or neurodegenerative diseases. Knowledge and disclosure of these cases is essential for a comprehensive management of biological therapy in our patients.
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