Radiofrequency ablation of symptomatic cervical inlet patch using a through-the-scope device: a pilot study

Area of Science:

• Gastroenterology
• Endoscopy
• Medical Devices

Background:

• Cervical inlet patch (CIP) is heterotopic gastric mucosa in the esophagus.
• CIP can cause chronic globus sensation and sore throat.
• Previous studies showed symptom improvement with argon plasma coagulation ablation.

Purpose of the Study:

• To assess a through-the-scope radiofrequency ablation (RFA) catheter for symptomatic CIP.
• Evaluate the safety and efficacy of RFA in treating CIP.

Main Methods:

• Ten patients with symptomatic CIP underwent RFA.
• A protocol of 3 ablations at 12 J/cm² was used per session.
• A maximum of 2 RFA sessions were allowed, with follow-up up to 12 months.

Main Results:

• 80% of patients achieved complete endoscopic and histologic resolution of CIP.
• Significant improvement in globus sensation, sore throat, and cough was observed.
• No adverse events like strictures or buried glands were identified.

Conclusions:

• Through-the-scope RFA is a safe and effective treatment for symptomatic CIP.
• One-year follow-up suggests durable resolution of CIP and symptom improvement.