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Related Experiment Video

Updated: Mar 18, 2026

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
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Nursing knowledge: hints from the placebo effect.

Renzo Zanotti1, Daniele Chiffi1

  • 1Department of Molecular Medicine, Laboratory of Evidence Based and Nursing Studies, University of Padova, Padova, Italy.

Nursing Philosophy : an International Journal for Healthcare Professionals
|July 5, 2016
PubMed
Summary

Nursing knowledge integrates general scientific findings with specific patient cases. An emergentist model, emphasizing a two-way flow, better explains phenomena like the placebo effect in nursing practice.

Keywords:
beliefsepistemologynursing knowledgeplacebo effectvalues

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Last Updated: Mar 18, 2026

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Area of Science:

  • Nursing Science
  • Philosophy of Science

Background:

  • Nursing knowledge development involves general scientific principles and specific clinical experiences.
  • The classical biomedical model (cascade model) applies population-level knowledge directly to individual cases.
  • An emergentist model proposes a dynamic, two-way interaction between general and specific knowledge.

Purpose of the Study:

  • To compare the cascade model with an emergentist model for nursing knowledge translation.
  • To explore the role of epistemic and non-epistemic values in nursing knowledge.
  • To analyze the placebo effect as an example of emergentist knowledge in nursing.

Main Methods:

  • Conceptual analysis comparing knowledge translation models.
  • Examination of the placebo effect within biomedical and emergentist frameworks.
  • Discussion of interactive, situated, and higher-order beliefs influencing the placebo effect.

Main Results:

  • The emergentist model offers a more comprehensive explanation for nursing knowledge, particularly phenomena like the placebo effect.
  • The placebo effect is influenced by patient-provider relationships, clinical context, and shared beliefs.
  • Nurses play a crucial role in managing placebo and nocebo effects.

Conclusions:

  • An emergentist approach, acknowledging a two-way flow of knowledge, is better suited for understanding nursing practice.
  • The placebo effect highlights the importance of context, relationships, and beliefs in healthcare.
  • There is a significant and inherent connection between the placebo effect and the evolution of nursing knowledge.