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Updated: Mar 18, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Clostridium difficile-associated disease: A primary clinical evaluation of elderly patients in a geriatric hospital
Arthur Leibovitz1, Alexandra Yarovoy1, Nataly Sharshar1
1Shmuel Harofeh Geriatric Medical Center affiliated with Sackler School of Medicine, Tel-Aviv University, Israel.
Abstract:
The purpose of this study was to screen all cases of Clostridium difficile-associated disease during a 2-year period in a geriatric hospital to determine the incidence and clinical characteristics related to this risk. Twenty percent of suspected cases were diagnosed as positive and analyzed. The C difficile disease-associated clinical factors were ischemic heart disease and chronic obstructive pulmonary disease. Use of acetylsalicylic acid, other nonsteroidal anti-inflammatory drugs, and steroids were more frequently found in the non-C difficile group. There were fewer cases in men than in women and more in patients residing in skilled nursing wards.
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