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Accurate Prediction of the Statistics of Repetitions in Random Sequences: A Case Study in Archaea Genomes
Mireille Régnier1, Philippe Chassignet2
1Inria, Palaiseau, France; LIX, Ecole Polytechnique, Palaiseau, France.
Abstract:
Repetitive patterns in genomic sequences have a great biological significance and also algorithmic implications. Analytic combinatorics allow to derive formula for the expected length of repetitions in a random sequence. Asymptotic results, which generalize previous works on a binary alphabet, are easily computable. Simulations on random sequences show their accuracy. As an application, the sample case of Archaea genomes illustrates how biological sequences may differ from random sequences.
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