Related Experiment Video
Updated: Mar 3, 2026
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Is a second look necessary in multiple and/or large Ta tumors?
Sıtkı Ün1, Hakan Türk, Mustafa Karabıçak
1Katip Çelebi University Atatürk Research and Training Hospital, Department of Urology, Izmir. sitki@doctor.com.
Introduction:
Most of the bladder cancers are tumors without muscle invasion at the time of diagnosis. Transurethral resection is the standard treatment in bladder tumors without muscle invasion. Proper review of transurethral resection is important for correct risk classification. In this study, our main objective was to show that a "second look" in patients with multiple and/or > 3 cm tumors regardless of T stage during the early term can be helpful in detection of possible residues and determining risk classification.
Materials And Methods:
156 patients with primary, multiple and/or > 3 cm tumors were included in the study. Patients were divided into 3 groups as Group 1 (Ta), Group 2 (T1 without second TUR) and Group 3 (T1 with second TUR). Macroscopic tumor occurrence rates were compared in their 3rd month control cystoscopy.
Results:
Macroscopic tumor detection rates in patients' 3rd month control cystoscopy were 21 (46.7%) in Group 1, 18 (30%) in Group 2 and 4 (7.8%) in Group 3. When compared with Group 3 patients, Group 1 and Group 2 had higher statistically significant macroscopic tumor detection rates (p = 0.001) CONCLUSION: A second look in patients with multiple and/or > 3 cm tumors during early term will enable the surgeons to detect possible tumors and do a better job in risk classification.
Insights
A second look transurethral resection (TUR) in patients with multiple or large bladder tumors improves early detection of residual disease. This follow-up procedure aids in more accurate risk classification for non-muscle invasive bladder cancer.
Area of Science:
- Urology
- Oncology
- Surgical Pathology
Background:
- Non-muscle invasive bladder cancer (NMIBC) is common at diagnosis.
- Transurethral resection (TUR) is the standard treatment for NMIBC.
- Accurate risk stratification is crucial for effective NMIBC management.
Purpose of the Study:
- To evaluate the utility of a "second look" TUR for NMIBC.
- To assess the impact of early follow-up TUR on detecting residual tumors.
- To determine if this approach improves risk classification for multiple or large NMIBC.
Main Methods:
- 156 patients with primary, multiple, and/or >3 cm NMIBC tumors were studied.
- Patients were categorized into three groups: Ta, T1 without second TUR, and T1 with second TUR.
- Macroscopic tumor recurrence rates were compared at 3-month cystoscopy.
Main Results:
- Macroscopic tumor detection rates at 3 months were significantly higher in the Ta (46.7%) and T1 without second TUR (30%) groups compared to the T1 with second TUR group (7.8%).
- The p-value was 0.001, indicating statistical significance.
- A second look TUR demonstrated a lower rate of residual tumor detection.
Conclusions:
- Early "second look" transurethral resection is beneficial for patients with multiple or large NMIBC.
- This strategy aids in the detection of residual tumors.
- It enhances the accuracy of risk classification for NMIBC patients.
