Related Experiment Video
Updated: Mar 18, 2026

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Indoles Using Visible-Light Catalysis
Meng Li1, Ji Yang1, Xuan-Hui Ouyang1
1State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University , Changsha 410082, China.
Abstract:
A new intermolecular 1,2-alkylarylation of styrenes with α-carbonyl alkyl bromides and indoles using fac-[Ir(ppy)3] as the photoredox catalyst has been developed. The method allows the simultaneous formation of two new carbon-carbon bonds through three component reaction, and represents a new single-electron transfer (SET) strategy for the 1,2-alkylarylation of the styrenes with broad substrate scope and excellent functional group tolerance.
More Related Videos
Related Concept Videos
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.
Halogenation of Alkenes
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)