Related Experiment Video
Updated: Mar 18, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Bipolar and related disorders in DSM-5 and ICD-10
Alexander Kaltenboeck1, Dietmar Winkler1, Siegfried Kasper1
1Department of Psychiatry and Psychotherapy,Medical University of Vienna,Vienna,Austria.
Abstract:
Bipolar disorders are a group of psychiatric disorders with profound negative impact on affected patients. Even if their symptomatology has long been recognized, diagnostic criteria have changed over time and diagnosis often remains difficult. The Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), issued in May 2013, comprises several changes regarding the diagnosis of bipolar disorders compared to the previous edition. Diagnostic categories and criteria for bipolar disorders show some concordance with the internationally also widely used Tenth Edition of the International Statistical Classification of Diseases and Related Health Problems (ICD-10). However, there are also major differences that are worth highlighting. The aim of the following text is to depict and discuss those.
Related Concept Videos
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Bipolar Disorder
Mania and Antimanic Drugs: Overview
Depressive Disorders: MDD and Dysthymia
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

