Related Experiment Video
Updated: Mar 18, 2026

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
Published on: April 5, 2018
ChAsE: chromatin analysis and exploration tool
Hamid Younesy1, Cydney B Nielsen2, Matthew C Lorincz3
1Graphics Usability and Visualization Lab, Simon Fraser University, Burnaby, Canada Canada's Michael Smith Genome Sciences Centre, Vancouver, Canada Biomedical Research Centre, University of British Columbia, Vancouver, Canada.
Abstract:
: We present ChAsE, a cross-platform desktop application developed for interactive visualization, exploration and clustering of epigenomic data such as ChIP-seq experiments. ChAsE is designed and developed in close collaboration with several groups of biologists and bioinformaticians with a focus on usability and interactivity. Data can be analyzed through k-means clustering, specifying presence or absence of signal in epigenetic data and performing set operations between clusters. Results can be explored in an interactive heat map and profile plot interface and exported for downstream analysis or as high quality figures suitable for publications.
Availability And Implementation:
Software, source code (MIT License), data and video tutorials available at http://chase.cs.univie.ac.at CONTACT: : mkarimi@brc.ubc.ca or torsten.moeller@univie.ac.atSupplementary information: Supplementary data are available at Bioinformatics online.
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