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Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

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Icarus: visualizer for de novo assembly evaluation.

Alla Mikheenko¹, Gleb Valin², Andrey Prjibelski¹

¹Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia, 199034.

Bioinformatics (Oxford, England)

|July 6, 2016

Summary

This summary is machine-generated.

Icarus is a new genome visualizer designed for assessing draft genome assemblies. This tool aids in the analysis of genomic data, offering improved visualization for de novo genome assembly evaluation.

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Area of Science:

Genomics
Bioinformatics
Computational Biology

Background:

Next-generation sequencing (NGS) generates vast amounts of data, making data visualization crucial for analysis.
Evaluating de novo genome assemblies is a key area in genomics research.
Existing visualization tools are often inadequate for comprehensive genome assembly assessment.

Purpose of the Study:

To introduce Icarus, a novel genome visualizer.
To provide accurate assessment and analysis of genomic draft assemblies.
To offer a visualization solution suitable for both model and non-model organisms.

Main Methods:

Development of Icarus, a genome visualizer.
Integration with the QUAST tool for quality assessment.
Implementation for both online and standalone use.

Main Results:

Icarus provides accurate assessment and analysis of genomic draft assemblies.
The tool is applicable to studies with or without a related reference genome.
Icarus enhances the evaluation of de novo genome assemblies.

Conclusions:

Icarus addresses the limitations of existing tools for genome assembly visualization.
The developed visualizer facilitates improved genomic data analysis.
Icarus is a valuable tool for researchers in genomics and bioinformatics.