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Updated: Mar 18, 2026

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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
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[Intraoperative optical coherence tomography in retinal detachment]
B Junker1, M Maier2, H Agostini3
1Universitätsklinik für Augenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. junker.bernd@mh-hannover.de.
Summary
Intraoperative optical coherence tomography (iOCT) provides detailed views of retinal detachment, revealing subretinal fluid and macular holes. While not yet proven to alter surgical decisions, iOCT offers insights into retinal microarchitecture.
Area of Science:
- Ophthalmology
- Surgical Technology
- Retinal Imaging
Background:
- Intraoperative optical coherence tomography (iOCT) is valuable in macular surgery and lamellar keratoplasty.
- Its specific benefits in retinal detachment surgery remain under investigation.
Purpose of the Study:
- To evaluate the utility of iOCT in retinal detachment surgery.
- To determine if iOCT findings influence therapeutic decisions and postoperative outcomes.
Main Methods:
- Analysis of published data (11 patients) and new data (23 patients) using iOCT during retinal detachment surgery.
- Correlation of iOCT findings with surgical interventions and patient outcomes.
Main Results:
- Outer retinal corrugations are common on iOCT during retinal detachment, persisting even with heavy liquid use.
- Significant subfoveal fluid is detected by iOCT, even when the retina appears reattached.
- Subclinical full-thickness macular holes are frequently observed in macula-off retinal detachments, potentially impacting visual prognosis.
Conclusions:
- iOCT offers detailed insights into the microarchitecture of the detached retina.
- Further research is needed to confirm if iOCT improves surgical decision-making and patient prognosis in retinal detachment repair.

