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Published on: April 19, 2019
Patient-Centred Care of Older Adults With Cardiovascular Disease and Multiple Chronic Conditions
Dae Hyun Kim1, Michael W Rich2
1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA; Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Insights
Managing multiple chronic conditions in older adults with cardiovascular disease requires a patient-centered approach. This strategy optimizes essential treatments, minimizes harm from polypharmacy, and improves quality of life.
Area of Science:
- Gerontology
- Cardiology
- Clinical Medicine
Background:
- Multimorbidity, the presence of two or more chronic conditions, is prevalent in older adults with cardiovascular disease (CVD).
- These patients face increased risks of adverse health outcomes and high healthcare utilization.
- Managing multimorbidity in CVD presents challenges due to patient heterogeneity, complex regimens, limited evidence, and fragmented care.
Purpose of the Study:
- To outline a patient-centered approach for managing older adults with cardiovascular disease and multimorbidity.
- To guide clinicians in optimizing treatment strategies for this complex patient population.
- To enhance the quality of life and functional status in elderly patients with multiple chronic conditions.
Main Methods:
- Review of clinical practice guidelines and evidence for managing cardiovascular disease in the context of multimorbidity.
- Emphasis on a patient-centered strategy integrating individual preferences, prognosis, and treatment feasibility.
- Discussion of optimizing adherence, managing polypharmacy, and considering drug-drug/drug-disease interactions.
Main Results:
- Current guidelines for single diseases may lead to impractical or harmful combined regimens in multimorbidity.
- A patient-centered approach can maximize benefits and minimize harms by prioritizing essential treatments.
- Individualized treatment decisions should consider the prognosis and time horizon for benefits versus harms.
Conclusions:
- A patient-centered approach is crucial for effectively managing older adults with cardiovascular disease and multimorbidity.
- Optimizing treatment involves prioritizing essential therapies and potentially discontinuing non-essential or harmful medications.
- Focusing on aspects of health that most impact functioning and quality of life is key to successful outcomes.
Abstract:
Multimorbidity, defined as the presence of 2 or more chronic conditions, is common among older adults with cardiovascular disease. These individuals are at increased risk for poor health outcomes and account for a large proportion of health care utilization. Clinicians are challenged with the heterogeneity of this population, the complexity of the treatment regimen, limited high-quality evidence, and fragmented health care systems. Each treatment recommended by a clinical practice guideline for a single cardiovascular disease might be rational, but the combination of all evidence-based recommendations can be impractical or even harmful to individuals with multimorbidity. These challenges can be overcome with a patient-centred approach that incorporates the individual's preferences, relevant evidence, the overall and condition-specific prognosis, clinical feasibility of treatments, and interactions with other treatments and coexisting chronic conditions. The ultimate goal is to maximize benefits and minimize harms by optimizing adherence to the most essential treatments, while acknowledging trade-offs between treatments for different health conditions. It might be necessary to discontinue therapies that are not essential or potentially harmful to decrease the risk of drug-drug and drug-disease interactions from polypharmacy. A decision to initiate, withhold, or stop a treatment should be on the basis of the time horizon to benefits vs the individual's prognosis. In this review, we illustrate how cardiologists and general practitioners can adopt a patient-centred approach to focus on the aspects of cardiovascular and noncardiovascular health that have the greatest effect on functioning and quality of life in older adults with cardiovascular disease and multimorbidity.
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