Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The polymerase chain reaction and its applications.

A Milbourne, S Nakamura, J M Nakamura

    Hawaii Medical Journal
    |April 1, 1989
    PubMed
    Summary

    Recombinant DNA technology enables prenatal screening for genetic defects. However, detecting subtle DNA changes remains a challenge due to limited molecular biology technique sensitivity.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Addressing high cervical cancer rates in the Rio Grande Valley along the Texas-Mexico border: a community-based initiative focused on education, patient navigation, and medical provider training/telementoring.

    Perspectives in public health·2021
    Same author

    Perspectives on cervical cancer screening and prevention: challenges faced by providers and patients along the Texas-Mexico border.

    Perspectives in public health·2018
    Same author

    Immunohistochemical detection of desmosomes in oral squamous cell carcinomas: correlation with differentiation, mode of invasion, and metastatic potential.

    International journal of oral and maxillofacial surgery·1992
    Same author

    [A case of eosinophilic pneumonia with diffuse reticular shadows and scattered nodular shadows on chest X-ray film--comparison of findings of chest X-ray and lung histology].

    Nihon Kyobu Shikkan Gakkai zasshi·1992
    Same author

    Susceptibility of methicillin-resistant Staphylococcus aureus clinical isolates to various antimicrobial agents. II. Isolation of arbekacin-resistant strain.

    Hiroshima journal of medical sciences·1992
    Same author

    Importance of HLA-DRB1 genotyping in cadaveric renal transplantation.

    Transplantation proceedings·1992

    Area of Science:

    • Molecular Biology
    • Genetics
    • Biotechnology

    Background:

    • Recombinant DNA technology has revolutionized genetic defect detection.
    • Prenatal screening for fetal DNA is now possible.
    • Congenital diseases can be identified through genetic analysis.

    Purpose of the Study:

    • To highlight advancements in genetic defect detection using recombinant DNA technology.
    • To discuss the application of these techniques in prenatal screening.
    • To address the limitations in detecting small DNA alterations.

    Main Methods:

    • Utilizing recombinant DNA technology for genetic analysis.
    • Employing molecular biology techniques for DNA screening.
    • Focusing on methods for detecting genetic defects in fetuses.

    Main Results:

    • New techniques allow for prenatal screening of fetal DNA.
    • Genetic defects leading to congenital diseases can be identified.
    • A significant challenge is the limited sensitivity for detecting minor DNA changes.

    Conclusions:

    • Recombinant DNA technology offers powerful tools for prenatal genetic diagnosis.
    • Improving the sensitivity of molecular biology techniques is crucial for comprehensive genetic screening.
    • Further research is needed to overcome sensitivity limitations in detecting small DNA variations.

    Related Experiment Videos