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Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
Dina Ismail1, Vidya Madhwapathi1, Evmorfia Ladoyanni1
1Department of Dermatology, Dudley Group NHS Foundation Trust, Dudley, West Midlands DY1 2HQ, UK.
A rare case reveals that excessive sweating of the buttocks and thighs may signal a urinary tract infection (UTI). Treating the UTI resolved the hyperhidrosis, suggesting a link between bladder pressure and sweating.
Area of Science:
- Urology
- Dermatology
- Internal Medicine
Background:
- Hyperhidrosis is excessive sweating beyond thermoregulation needs, occurring primarily or secondarily.
- Secondary hyperhidrosis can result from neurogenic sympathetic overactivity affecting eccrine glands.
Purpose of the Study:
- To report a unique case of new-onset focal hyperhidrosis linked to recurrent urinary tract infections (UTIs).
- To investigate the potential association between lower urinary tract symptoms and secondary hyperhidrosis.
Main Methods:
- Case report of a 75-year-old male with focal hyperhidrosis.
- Urological investigation including assessment for urethral strictures and cystitis.
- Correlation of hyperhidrosis symptoms with culture-positive Escherichia coli (E. coli) urine samples and treatment response.
Main Results:
- The patient presented with secondary focal hyperhidrosis of the buttocks, pelvis, and upper thighs.
- Symptoms correlated with culture-positive E. coli UTIs.
- Hyperhidrosis resolved with antibiotic treatment for UTIs and stabilized with prophylactic antibiotics.
Conclusions:
- Urethral strictures may lead to voiding inhibition, increasing UTI susceptibility.
- Increased bladder pressure from urine accumulation might trigger sympathetic discharge, causing hyperhidrosis.
- Recommends urine dipstick tests for new-onset focal hyperhidrosis in these areas and timely urological referral for males with recurrent UTIs.
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