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Ole Isacson: Development of New Therapies for Parkinson's Disease
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Ole Isacson: Development of New Therapies for Parkinson's Disease

Published on: April 29, 2007

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A potential case of remission of Parkinson's disease

Karishma Smart, Raymon Durso, Jonathan Morgan

    Journal of Complementary & Integrative Medicine
    |July 6, 2016
    PubMed

    Insights

    This case study details a Parkinson's disease (PD) patient who experienced symptom remission for over a decade. Long-term meditation practice may have contributed to this unexpected improvement.

    Area of Science:

    • Neurology
    • Neuroscience
    • Dopamine Research

    Background:

    • Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms like tremor and gait disturbances.
    • Current treatments primarily manage symptoms but do not halt disease progression.

    Observation:

    • A 78-year-old male diagnosed with PD 16 years prior presented with classic motor symptoms.
    • After initial progression, his symptoms significantly improved and have been in remission since 2012, with no medication use.
    • Diagnostic confirmation included clinical presentation, Sinemet response, and SPECT DaT scan.

    Findings:

    • This case suggests the potential for spontaneous or treatment-adjuvant-induced remission of Parkinson's disease symptoms.
    • The patient's extensive history of meditation practice is proposed as a potential contributing factor to symptom improvement.

    Implications:

    • Further research into meditation's neurobiological effects, particularly dopamine release in the striatum, is warranted.
    • This case may open new avenues for exploring non-pharmacological interventions in managing Parkinson's disease.

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