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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Oncologic Outcomes After Nipple-Sparing Mastectomy.
Tracy Ann Moo1, Tiffany Pinchinat2, Simone Mays1
1Department of Surgery, Weill Cornell Medicine, New York, NY, USA.
Annals of Surgical Oncology
|July 7, 2016
Summary
Nipple-sparing mastectomy (NSM) shows promising oncologic safety for breast cancer treatment, with a 3-year recurrence-free survival rate of 93.6%. Further long-term follow-up is needed to confirm these findings for breast cancer patients.
Area of Science:
- Oncology
- Surgical Oncology
- Breast Cancer Research
Background:
- Nipple-sparing mastectomy (NSM) offers improved aesthetics compared to traditional mastectomy.
- Limited data exist on the oncologic safety of NSM.
- NSM has been performed for oncologic and prophylactic reasons over the past decade.
Purpose of the Study:
- To evaluate the oncologic outcomes of nipple-sparing mastectomy (NSM) in breast cancer patients.
- To assess recurrence rates and survival following NSM for breast cancer.
- To contribute data on the oncologic safety of NSM.
Main Methods:
- Retrospective review of NSM cases from July 2007 to July 2013.
- Descriptive statistics to characterize the patient cohort.
- Kaplan-Meier survival analysis to estimate recurrence-free survival.
Main Results:
- 721 NSMs were performed on 413 patients; 89.1% were for breast cancer.
- The 3-year recurrence-free survival rate was 93.6% in the breast cancer group.
- Locoregional recurrence rate was 2.2%, with distant recurrence at 2.4%.
Conclusions:
- NSM demonstrates promising oncologic outcomes for breast cancer treatment.
- The overall recurrence rate was 6.3%, with most recurrences being distant.
- Longer follow-up is required to fully ascertain the long-term oncologic safety of NSM.
