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Updated: Mar 18, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
Year in Review 2015: Pediatric ARDS.
1Division of Critical Care Medicine, Department of Pediatrics, Duke Children's Hospital, Duke University Medical Center, Durham, North Carolina. ira.cheifetz@duke.edu.
In 2015, significant advancements were made in understanding pediatric acute respiratory distress syndrome (ARDS). Further research is crucial for improving outcomes in children with this critical lung condition.
Area of Science:
- Pediatric critical care medicine
- Pulmonology
- Neonatology
Background:
- Pediatric acute respiratory distress syndrome (ARDS) management knowledge lags behind adult care.
- 2015 saw a notable increase in publications regarding pediatric ARDS.
- The Pediatric Acute Lung Injury Consensus Conference (PALICC) has driven recent progress.
Purpose of the Study:
- To review key 2015 publications on pediatric ARDS.
- To highlight advancements in diagnosis and management strategies for pediatric ARDS.
- To identify areas requiring further investigation in pediatric ARDS.
Main Methods:
- Literature review focusing on 2015 publications.
- Emphasis on consensus definitions, ventilation strategies, and adjunctive therapies.
- Analysis of sedation, delirium, and noninvasive support in pediatric ARDS.
Main Results:
- The PALICC consensus definition provides a framework for pediatric ARDS.
- Key areas of focus included high-frequency oscillatory ventilation and lung-protective strategies.
- Progress was made in understanding sedation and delirium management.
Conclusions:
- Recent publications have significantly expanded the literature on pediatric ARDS.
- Continued research is essential for improving treatment and outcomes for children with ARDS.
- Further investigation is needed in ventilation, sedation, and delirium management.
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