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Infantile Tremor Syndrome Persistence in Era of Development: An Old Story

Anand Kumar1, Gayathri M Rao1, Beena V Shetty1

  • 1Department of Biochemistry, Center for Basic Sciences, Kasturba Medical College, Bejai, Mangalore, Karnataka 575004 India.

Indian Journal of Clinical Biochemistry : IJCB
|July 7, 2016
PubMed

Insights

Infantile tremor syndrome (ITS) persists despite malnutrition programs. This case highlights severe ITS with neurological and hematological issues in a young child.

Area of Science:

  • Pediatrics
  • Neurology
  • Hematology

Background:

  • Infantile tremor syndrome (ITS) is prevalent globally, particularly in developing nations.
  • Despite ongoing protein-energy malnutrition awareness programs, ITS persists, indicating a need for further research and intervention.

Observation:

  • A 13-month-old female presented with respiratory distress, fever, limb tremors, and loss of developmental milestones.
  • Clinical examination revealed pallor and hyperpigmentation in the axilla and toes.

Findings:

  • Investigative findings included megaloblastic erythroid hyperplasia and severe anemia (hemoglobin 1.6 g%).
  • Brain CT scan demonstrated central atrophic changes, suggesting neurological involvement.

Implications:

  • This case underscores the critical need for early diagnosis and comprehensive management of ITS.
  • Highlighting the neurological and hematological complications of ITS is crucial for improving patient outcomes and public health strategies.

Keywords:
FolateInfantile tremor syndromeMalnutritionVitamin B12

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