Related Experiment Video
Updated: Mar 18, 2026

Author Spotlight: Treating Frozen Shoulder with Small Needle Knife Therapy
Published on: November 17, 2023
Miniscalpel-Needle Treatment Is Effective for Work-Related Neck and Shoulder Musculoskeletal Disorders
Shuming Li1, Tong Shen2, Yongshan Liang2
1Department of Rehabilitation Medicine, First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China; Department of Orthopedics Medicine, First Affiliated Hospital of Guangzhou Medical University, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China; Department of Orthopedics Medicine, Beijing Fengsheng Special Hospital of Traditional Medical Traumatology and Orthopaedics, No. 306, Fuchengmen Street, Beijing 100034, China; Guangdong Key Laboratory of Orthopaedic Technology and Implant Materials, No. 151, Yanjiang West Road, Guangzhou, Guangdong 510120, China.
Abstract:
Background. Work-related musculoskeletal disorders (MSDs) are a group of painful disorders of muscles, tendons, and nerves, such as neck and shoulder MSD. This study was designed to use miniscalpel-needle (MSN) technique as an intervention for work-related MSDs. Methods. Thirty-one patients with work-related MSDs and 28 healthy subjects were enrolled as controls in this study. The MSD symptoms of each patient were assessed by visual analog scale (VAS) and neck disability index (NDI). Blood samples were collected from control subjects and MSD patients before and after treatment. Serum levels of C-reactive protein (CRP) and tumor necrosis factor (TNF) were measured using ELISA. Results. Prior to MSN treatment, serum levels of CRP and TNF were significantly higher in the MSD patients than the healthy controls. Serum CRP levels correlated with VAS and NDI scores, and serum TNF levels correlated with NDI scores. Compared to pretreatment, VAS and NDI scores were significantly lower in MSD patients after MSN treatment, while serum CRP and TNF levels were significantly lower compared with the healthy control levels. Conclusions. Our results indicate that MSN may be an effective intervention for work-related MSDs and be associated with lower serum levels of inflammatory biomarkers.

