[Primary Study on Noninvasive Detection of Vascular Function Based on Finger Temperature Change]

Area of Science:

• Biomedical Engineering
• Cardiovascular Research
• Non-invasive Diagnostics

Background:

• Cardiovascular diseases pose a significant health burden.
• Early detection of vascular dysfunction is crucial for prevention.
• Existing methods for assessing vascular function can be invasive or limited.

Purpose of the Study:

• To develop and validate a novel non-invasive method for assessing vascular function.
• To investigate the relationship between fingertip temperature changes and arterial function.
• To provide a tool for the early diagnosis and prevention of cardiovascular diseases.

Main Methods:

• Customized hardware modules for blood occlusion, finger temperature, and blood oxygen acquisition.
• Data acquisition system programmed using Labview software.
• Collected physiological data, including fingertip temperature, blood oxygen, and blood pressure, from healthy subjects and patients with cardiovascular diseases.

Main Results:

• Extracted 12 parameters from fingertip temperature signals using time-domain analysis.
• Identified 8 significant parameter differences between healthy subjects and those with cardiovascular diseases.
• Developed a discriminant function for vascular function status based on statistical analysis.

Conclusions:

• Changes in fingertip temperature during brachial artery occlusion are closely related to vascular function.
• The developed non-invasive method shows promise for early detection of vascular dysfunction.
• This method could lay the foundation for improved early detection strategies for cardiovascular diseases.