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Updated: Aug 5, 2026

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
Healing of laser-induced defects of articular cartilage: preliminary studies
M Borovoy1, R M Zirkin, L M Elson
1Department of Orthopedic Surgery, Sinai Hospital of Detroit, Michigan 48235.
Abstract:
The investigators have induced defects to the articular surfaces of knee joints in rabbits with the use of a CO2 laser. Subsequent healing of these defects have been studied and are described. This work has demonstrated healing with formation of fibrocartilage and hyaline cartilage in two of eight cases. Further investigation with improved techniques will be undertaken in order to produce effective healing on a more consistent basis. This article also reviews previous investigation related to the healing of cartilage defects.

