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Updated: Jul 31, 2026

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Expression of Bax Protein and Morphological Changes in the Myocardium in Experimental Acute Pressure Overload of the
M L Blagonravov1, A Yu Korshunova1, M M Azova2
1Department of Pathology and Pathological Physiology, Moscow, Russia.
Abstract:
The expression of Bax protein, marker of intracellular pathway of apoptosis initiation, in viable left ventricular cardiomyocytes and morphological changes in the myocardium in acute pressure overload of the left ventricle were studied in experiment on male rabbits. The content of Bax protein in the cardiomyocyte cytoplasm decreased, this indicating that the mitochondrial pathway was not involved in the realization of the apoptotic program. This decrease was associated with manifest destructive changes in the left ventricular myocardium.
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