Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fluorescent Detection of Aqueous <i>N</i>-Nitrosodimethylamine via Photochemical Transformation and Affinity Capture.

Journal of the American Chemical Society·2026

Same author

Shedding light on bacterial fitness in a tug-of-war with liquid crystal emulsions.

Nature communications·2026

Same author

Through-space donor-acceptor homoconjugation strategies for emissive radical species.

Chemical science·2026

Same author

Ultrasensitive Hydrogen Detection via Layered n-Type Polymer Chemiresistors.

Nano letters·2026

Same author

Photoactive PFA Coating through Fluorophilic Interactions for Continuous Flow Photochemistry.

JACS Au·2025

Same author

Stable Helical Assembly of Propellane-Based Polymers and Nanotube Composites.

ACS applied materials & interfaces·2025

Search research articles

Related Experiment Video

Updated: Mar 18, 2026

Preparation and Application of a New Bacterial Biosensor for the Presumptive Detection of Gunshot Residue

Preparation and Application of a New Bacterial Biosensor for the Presumptive Detection of Gunshot Residue

Published on: May 9, 2019

Wireless Hazard Badges to Detect Nerve-Agent Simulants.

Rong Zhu¹, Joseph M Azzarelli¹, Timothy M Swager²

¹Department of Chemistry and Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA, USA.

Angewandte Chemie (International Ed. in English)

|July 8, 2016

Summary

A new wearable hazard badge detects diethylchlorophosphate (DCP), an organophosphorus simulant. This single-use device offers a simple, wireless readout for monitoring chemical exposure, enabling real-time health risk assessment.

Keywords:

carbon nanotubes dosimeter ionic liquids nerve agents sensors

More Related Videos

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Published on: April 26, 2012

Related Experiment Videos

Last Updated: Mar 18, 2026

Preparation and Application of a New Bacterial Biosensor for the Presumptive Detection of Gunshot Residue

Preparation and Application of a New Bacterial Biosensor for the Presumptive Detection of Gunshot Residue

Published on: May 9, 2019

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Published on: April 26, 2012

Area of Science:

Environmental Science
Chemical Sensors
Nanotechnology

Background:

Chemical exposure poses significant health risks.
Organophosphorus compounds, like diethylchlorophosphate (DCP), are common hazardous chemicals.
Existing detection methods can be complex or lack real-time monitoring capabilities.

Purpose of the Study:

To develop a single-use wearable hazard badge for dosimetric detection of diethylchlorophosphate (DCP).
To create a sensor platform with a wireless readout for easy monitoring of chemical exposure.
To establish a cost-effective and manufacturable sensor for organophosphorus detection.

Main Methods:

Fabrication of improved chemically actuated resonant devices (CARDs) in a single step.
Development of an ionic-liquid-mediated single-walled carbon nanotube (SWCNT) based chemidosimetric scheme.
Integration of the sensor with a smartphone for wireless readout and irreversible change detection.

Main Results:

The developed sensor platform achieved DCP limits of detection of 28 ppb.
The badge provides a selective and readily manufacturable sensor element.
An 8-hour workday time-weighted average exposure of 10 ppb DCP resulted in an irreversible change in the smartphone readout.

Conclusions:

The single-use wearable hazard badge offers a promising solution for real-time, dosimetric detection of DCP.
The ionic-liquid-mediated SWCNT sensor demonstrates high sensitivity and selectivity for organophosphorus compounds.
This technology facilitates practical, on-site monitoring of hazardous chemical exposure, enhancing worker safety.