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Sequence-Specific Recognition of DNA by Proteins: Binding Motifs Discovered Using a Novel Statistical/Computational

David Jakubec1,2, Roman A Laskowski3, Jiri Vondrasek1

  • 1Institute of Organic Chemistry and Biochemistry, Prague 6, Czech Republic.

Plos One
|July 8, 2016
PubMed
Summary

This study reveals new energetic criteria for protein-DNA recognition, identifying additional amino acid motifs that distinguish DNA bases beyond direct readout. These findings offer a more general understanding of DNA sequence specificity.

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