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Updated: Mar 18, 2026

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
Published on: August 31, 2022
Postradiation Dermatofibrosarcoma Protuberans: Case Report and Literature Review
C-T Lin1, S-C Chang1, T-M Chen1
1a Division of Plastic and Reconstructive Surgery, Department of Surgery , Taipei , Taiwan.
Abstract:
Radiotherapy has long been known to induce soft tissue sarcomas. However, there are only six cases of post-radiation dermatofibrosarcoma protuberans (DFSP) reported in the literature, and no case in Asians has been reported so far. Herein, we report a case of DFSP, confirmed by immunohistochemistry, which developed on the old scar at the irradiated right chest wall of an Asian woman. We performed a radical surgical excision of the lesion and covered the defect with latissimus dorsi island myocutaneous flap followed the surgical treatment. 12 months postoperatively, the patient leads a good result without signs of recurrence.

