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Postradiation Dermatofibrosarcoma Protuberans: Case Report and Literature Review
C-T Lin1, S-C Chang1, T-M Chen1
1a Division of Plastic and Reconstructive Surgery, Department of Surgery , Taipei , Taiwan.
Acta Chirurgica Belgica
|July 8, 2016
Summary
This study reports the first case of post-radiation dermatofibrosarcoma protuberans (DFSP) in an Asian patient. The rare soft tissue sarcoma developed on a scar after radiotherapy, with successful surgical removal and no recurrence after 12 months.
Area of Science:
- Oncology
- Dermatology
- Surgical Oncology
Background:
- Radiotherapy is a known risk factor for secondary soft tissue sarcomas.
- Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer, and post-radiation cases are exceptionally uncommon.
- No previous reports exist of DFSP developing in an Asian patient following radiotherapy.
Observation:
- A case of DFSP is presented in an Asian woman.
- The tumor arose on an old scar located on the right chest wall, an area previously treated with radiotherapy.
- Diagnosis was confirmed through immunohistochemistry.
Findings:
- The patient underwent radical surgical excision of the DFSP.
- Reconstruction of the chest wall defect was achieved using a latissimus dorsi island myocutaneous flap.
- Postoperative follow-up at 12 months showed no signs of tumor recurrence.
Implications:
- This case expands the understanding of radiotherapy-induced malignancies.
- It highlights the importance of vigilance for rare secondary malignancies in irradiated areas, even in diverse ethnic populations.
- The successful surgical management demonstrates effective treatment strategies for this rare presentation.
