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Updated: Mar 18, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

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Subclinical LV Dysfunction Detection Using Speckle Tracking Echocardiography in Hypertensive Patients with Preserved

Amal Mohamed Ayoub1, Viola William Keddeas1, Yasmin Abdelrazek Ali1

  • 1Cardiology Department, Ain Shams University, Cairo, Egypt.

Clinical Medicine Insights. Cardiology
|July 8, 2016
PubMed

Insights

Early detection of subclinical systolic dysfunction in hypertensive patients is crucial. Two-dimensional speckle tracking echocardiography (2D-STE) identified impaired left ventricular (LV) function in hypertensive individuals with preserved ejection fraction (EF), enabling earlier intervention.

Area of Science:

  • Cardiology
  • Echocardiography
  • Hypertension Research

Background:

  • Hypertensive heart disease progression can be prevented by early detection of subclinical left ventricular (LV) systolic dysfunction.
  • Subclinical LV systolic dysfunction is a critical indicator in hypertensive patients.

Purpose of the Study:

  • To assess the utility of two-dimensional speckle tracking echocardiography (2D-STE) in detecting subclinical LV systolic dysfunction in hypertensive patients.
  • To identify hypertensive patients with preserved left ventricular ejection fraction (LVEF) who exhibit impaired systolic function.

Main Methods:

  • Studied 60 hypertensive patients and 30 healthy controls, all with preserved LVEF.
  • Utilized two-dimensional speckle tracking echocardiography (2D-STE) for detailed systolic function assessment.
  • Compared global longitudinal strain and systolic velocity between groups.

Main Results:

  • No significant difference in ejection fraction (EF) by Simpson's method between groups.
  • Hypertensive patients showed significantly lower systolic velocity and global longitudinal strain compared to controls.
  • 2D-STE identified subclinical systolic dysfunction in 23 of 60 hypertensive patients (vs. 3 of 30 controls).

Conclusions:

  • 2D-STE effectively detects significant impairment of LV systolic function in hypertensive patients with preserved LVEF.
  • This method identifies high-risk subgroups requiring earlier medical intervention.
  • Early detection of subclinical dysfunction aids in managing hypertensive heart disease.
Abstract

Keywords:
global longitudinal strain (GLS)hypertensionspeckle tracking

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