Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypodermis01:02

Hypodermis

8.4K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
8.4K
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

7.2K
7.2K
Regulation of Metabolism01:19

Regulation of Metabolism

12.1K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
12.1K
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

6.5K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prenatal exercise interventions result in subtle changes in the human breast milk metabolome and lipidome 7-14 days postpartum: exploratory analyses of the FitMum randomized controlled trial.

International breastfeeding journal·2026
Same author

Isolation of Extracellular Vesicles From Mouse Brown Adipose Tissue Secretome Using Size-Exclusion Chromatography.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Distinct Effects of Maternal Stress and Exercise on Offspring Metabolic Health.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

How to train your rodent: Recommendations for the preclinical study of exercise-induced benefits in metabolic research.

Cell metabolism·2026
Same author

Multi-omic responses to acute exercise in abdominal subcutaneous adipose tissue of sedentary adults: findings from MoTrPAC.

bioRxiv : the preprint server for biology·2026
Same author

Muscle movement and metabolism: exercise and skeletal muscle as mediators of health-a report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.

The American journal of clinical nutrition·2026

Related Experiment Video

Updated: Mar 18, 2026

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
06:08

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

3.0K

Exercise regulation of adipose tissue.

Kristin I Stanford1, Laurie J Goodyear2

  • 1Dorothy M. Davis Heart and Lung Research Institute, Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center , Columbus, OH, USA.

Adipocyte
|July 8, 2016
PubMed
Summary

Exercise training benefits metabolic health by adapting adipose tissue. This review explores how exercise influences white and brown adipose tissue, including the browning of white fat, to improve overall health.

Keywords:
beigingbrown adipose tissueexercisemyokineswhite adipose tissue

More Related Videos

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

15.9K
Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro
09:41

Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro

Published on: March 17, 2023

3.9K

Related Experiment Videos

Last Updated: Mar 18, 2026

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
06:08

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

3.0K
Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

15.9K
Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro
09:41

Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro

Published on: March 17, 2023

3.9K

Area of Science:

  • Exercise physiology
  • Adipose tissue biology
  • Metabolic health

Background:

  • Exercise training confers protection against metabolic disorders like obesity and type 2 diabetes.
  • Adipose tissue, including white adipose tissue (WAT) and brown adipose tissue (BAT), is increasingly recognized for its role in exercise's health benefits.
  • Exercise induces changes in WAT, such as reduced cell size and lipid content, and increased mitochondrial activity.

Purpose of the Study:

  • To review the mechanisms underlying exercise training-induced adaptations in adipose tissue.
  • To examine the effects of exercise on white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipocyte induction.
  • To investigate the factors contributing to exercise-induced beiging of human subcutaneous WAT (scWAT).

Main Methods:

  • Review of existing scientific literature on exercise training and adipose tissue.
  • Analysis of studies investigating exercise-induced changes in WAT and BAT in both rodents and humans.
  • Focus on studies elucidating the regulatory mechanisms of exercise-induced adipose tissue adaptations.

Main Results:

  • Exercise training leads to decreased adipocyte size and lipid content, and enhanced mitochondrial activity in WAT.
  • Exercise promotes the 'beiging' of WAT in rodents, a process currently under investigation in humans.
  • Data on exercise training's effects on BAT mass and function remain conflicting, requiring further research.

Conclusions:

  • Exercise training induces significant adaptations in adipose tissue, contributing to metabolic health.
  • The beiging of human WAT and the precise mechanisms regulating these adaptations are key areas for future research.
  • Further investigation is needed to resolve conflicting data regarding exercise's impact on brown adipose tissue.