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Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Breathing01:05

Breathing

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The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
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Subsequent T...
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Immunodeficiency Diseases01:25

Immunodeficiency Diseases

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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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Blistering diseases in neonates.

Cathy Y Zhao1, Dedee F Murrell

  • 1aDermatology, St George HospitalbMedicine, University of New South Wales, Sydney, Australia.

Current Opinion in Pediatrics
|July 9, 2016
PubMed
Summary

Neonatal blistering diseases require prompt diagnosis. Infections are common causes, necessitating early antimicrobial treatment, while autoimmune and inherited conditions require specific investigations and management strategies.

Area of Science:

  • Neonatal dermatology
  • Pediatric pathology
  • Clinical immunology

Background:

  • Neonatal blistering diseases are rare but can be life-threatening.
  • Accurate diagnosis is essential for appropriate management.
  • This review synthesizes current knowledge on causes and clinical approaches.

Purpose of the Study:

  • To review recent literature on neonatal blistering diseases.
  • To outline the differential diagnoses.
  • To guide the clinical approach to affected neonates.

Main Methods:

  • Literature review of recent publications.
  • Analysis of causes and clinical presentations.
  • Synthesis of diagnostic and therapeutic strategies.

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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
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Main Results:

  • Neonatal infections are the most frequent cause of blistering.
  • Autoimmune blistering diseases are rare in neonates.
  • Inherited genodermatoses, including epidermolysis bullosa, are also uncommon.

Conclusions:

  • Investigate blister fluid for infection and initiate antimicrobials promptly.
  • Consider autoimmune blistering diseases in neonates with maternal history.
  • Suspect inherited genodermatoses with family history; seek specialist advice and genetic testing.