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Related Concept Videos

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
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According to obedience research, we may harm others under the forceful pressures of an authority figure (Milgram, 1974). How about if the inappropriate orders were delivered with less force? The increasing interdependence between nurses and physicians compelled Hofling and his colleagues to explore nurses’ reactions to a potentially harmful medical request made by the perceived authority figure, the doctor (Hofling, Brotzman, Dalrymple, Graves, & Pierce, 1966). In this situation,...
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Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
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Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Related Experiment Video

Updated: Mar 18, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Pressure to prescribe antimicrobials.

Ruth Doherty

    British Dental Journal
    |July 9, 2016
    PubMed
    Summary

    Dentists in Wales participated in the first clinical audit of antimicrobial prescribing. This study assessed prescribing patterns to improve appropriate antibiotic use in dental practice.

    Area of Science:

    • Dentistry
    • Pharmacology
    • Public Health

    Background:

    • Antimicrobial resistance (AMR) is a significant global health threat.
    • Appropriate antimicrobial prescribing is crucial in all healthcare settings, including dentistry.
    • Clinical audits are essential for monitoring and improving prescribing practices.

    Purpose of the Study:

    • To evaluate the patterns of antimicrobial prescribing by dentists in Wales.
    • To identify areas for improvement in antibiotic stewardship within dental care.
    • To establish a baseline for future antimicrobial prescribing audits in Welsh dental practices.

    Main Methods:

    • A prospective clinical audit was conducted across dental practices in Wales.
    • Data on antimicrobial prescriptions were collected over a defined period.

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  • Prescribing data were analyzed against established guidelines for dental infections.

    • Main Results:

    • The audit identified variations in antimicrobial prescribing habits among dentists.
    • Specific antibiotic classes and treatment durations were noted.
    • Adherence to guidelines for common dental conditions was assessed.

    Conclusions:

    • The findings highlight the need for enhanced antimicrobial stewardship education for dentists in Wales.
    • Regular clinical audits are recommended to ensure optimal antimicrobial prescribing in dentistry.
    • Interventions may be necessary to reduce inappropriate antibiotic use and combat AMR.