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Transcutaneous Bilirubin Levels during the First Month of Life in Term and Late-preterm Newborns

Serdar Umit Sarici1, Omer Gunes2, Esad Koklu3

  • 1Division of Neonatology, Department of Pediatrics, Gulhane Military Medical Academy, Ankara-06018, Turkey.

Journal of Tropical Pediatrics
|July 9, 2016
PubMed

Insights

This study developed a transcutaneous bilirubin (TcB) nomogram for Turkish newborns to assess risks of jaundice. The nomogram helps predict significant hyperbilirubinemia and prolonged jaundice in the first month of life.

Area of Science:

  • Neonatal Medicine
  • Pediatrics
  • Medical Diagnostics

Background:

  • Hyperbilirubinemia is common in newborns, posing risks of significant jaundice.
  • Accurate risk assessment is crucial for timely intervention in term and late-preterm infants.
  • Existing nomograms may not be population-specific, necessitating localized data.

Purpose of the Study:

  • To develop a transcutaneous bilirubin (TcB) nomogram tailored for Turkish newborns.
  • To assess the risk of significant hyperbilirubinemia and prolonged jaundice in the first month of life.
  • To provide a tool for clinicians to manage neonatal jaundice effectively.

Main Methods:

  • Developed a nomogram based on daily transcutaneous bilirubin (TcB) measurements at 3, 7, 15, and 30 days.
  • Utilized a transcutaneous bilirubinometer (JaundiceDetector JH20-1C) for measurements.
  • Analyzed data from 729 healthy term and late-preterm Turkish infants aged 3-30 days.

Main Results:

  • A TcB nomogram was successfully developed for Turkish infants.
  • At 15 days, 41.98% of infants had TcB levels ≥5 mg/dl; at 30 days, 25.9% did.
  • The 97th percentile cutoff values were 11.4 mg/dl at 15 days and 10.0 mg/dl at 30 days.

Conclusions:

  • The developed TcB nomogram is a valuable tool for risk assessment in Turkish newborns.
  • It aids in identifying infants at risk for significant hyperbilirubinemia and prolonged jaundice.
  • The nomogram facilitates evidence-based clinical decision-making for neonatal jaundice management.
Abstract

Keywords:
first month.newbornnomogramtranscutaneous bilirubin

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