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Updated: Mar 18, 2026

Procedure for Fabricating Biofunctional Nanofibers
Published on: September 10, 2012
Biofunctionalizing nanofibers with carbohydrate blood group antigens
Katie Barr1, Bhuvaneswari Kannan2, Elena Korchagina3
1Centre for Kode Technology Innovation, School of Engineering Faculty of Design and Creative Technologies, Auckland University of Technology, Auckland, New Zealand.
Abstract:
A rapid and simple method of biofunctionalising nylon, cellulose acetate, and polyvinyl butyral electrospun nanofibers with blood group glycans was achieved by preparing function-spacer-lipid constructs and simply contacting them to fibers with a piezo inkjet printer. A series of water dispersible amphipathic glycan-spacer constructs were synthesized representing a range ABO and related blood group antigens. After immediate contact of the amphipathic glycan-spacer constructs with nanofiber surfaces they self-assembled and were detectable by enzyme immunoassays with high sensitivity and specificity.
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