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Management of Complications of Acute Otomastoiditis in Solid Organ Transplant Patients
Douglas Hildrew1, Austin Adams1, Ryan Winters1
1Tulane University Department of Otolaryngology - Head and Neck Surgery.
Insights
Solid organ transplant recipients with acute otomastoiditis require prompt recognition and aggressive treatment. Early intervention in these immunocompromised patients is crucial to prevent severe complications like meningitis and sepsis.
Area of Science:
- Otolaryngology
- Transplant Surgery
- Infectious Diseases
Background:
- Over 183,000 solid organ transplant recipients in the US face unique health risks.
- Acute otomastoiditis complications in this population are understudied.
- Immunocompromised status heightens susceptibility to severe infections.
Observation:
- A 63-year-old renal transplant recipient presented with otorrhea and altered mental status.
- The patient developed meningitis, sigmoid sinus thrombosis, and sepsis secondary to acute otitis media.
- Treatment involved antibiotics, tympanostomy tube, and mastoidectomy.
Findings:
- The patient experienced a severe progression of acute otomastoiditis.
- Aggressive multimodal treatment led to a full recovery without neurological deficits.
- This case highlights the potential severity of otomastoiditis in transplant patients.
Implications:
- Prompt recognition and treatment of acute otomastoiditis are vital in immunosuppressed patients.
- Aggressive management can prevent devastating intracranial and systemic complications.
- Further research is needed to establish specific guidelines for this population.
Background:
There are over 183,000 patients living with a functioning solid organ transplant in the United States, and almost no data exist discussing complications of acute otomastoiditis in this vulnerable population. Early recognition and treatment of acute otomastoiditis is essential in patients whose immune system is not normal, as progression can lead to sepsis, meningitis, brain abscess, Bezold's abscess, sigmoid sinus thrombosis, or other potentially fatal sequelae.
Methods:
Case report with extensive literature review.
Results:
A 63 year-old man presented 3 years after cadaveric renal transplant with otorrhea and altered mental status. His acute otitis media progressed to meningitis with sigmoid sinus thrombosis and sepsis, and management included IV and otic antibiotics, tympanostomy tube placement, and cortical mastoidectomy. The patient made a full recovery without residual neurologic deficit.
Conclusion:
Extrapolating data from patients immunosuppressed for other reasons, patients immunosuppressed after solid organ transplant should receive prompt recognition and aggressive treatment of acute otomastoiditis to prevent or address potentially devastating intracranial or systemic complications.
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