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Cystic fibrosis and sinusitis.

J P Cuyler1, A J Monaghan

  • 1Department of Surgery, Walter MacKenzie Health Sciences Centre, University of Alberta, Edmonton, Canada.

The Journal of Otolaryngology
|June 1, 1989
PubMed
Summary

Children with cystic fibrosis commonly have sinonasal disease. Coronal CT scans accurately identify this, and outpatient endoscopic sinus surgery is a safe, low-morbidity option for treatment.

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Area of Science:

  • Otolaryngology
  • Pediatric Pulmonology
  • Radiology

Background:

  • Cystic fibrosis (CF) is a genetic disorder affecting multiple organs, including the sinonasal tract.
  • Sinonasal disease, such as nasal polyposis and sinusitis, is frequently observed in CF patients.
  • Accurate diagnosis and effective treatment of sinonasal disease are crucial for managing CF patients' quality of life.

Purpose of the Study:

  • To evaluate the prevalence and characteristics of sinonasal disease in children with cystic fibrosis.
  • To compare the diagnostic accuracy of office examination, coronal CT scanning, and surgical findings.
  • To assess the safety and efficacy of outpatient functional endoscopic sinus surgery (FESS) in this population.

Main Methods:

  • Retrospective review of pediatric patients with CF from the University of Alberta Cystic Fibrosis Clinic.
  • Comparison of findings from clinical examinations, coronal CT scans, and intraoperative observations during FESS.
  • Analysis of surgical outcomes and morbidity associated with FESS compared to conventional sinus surgery.

Main Results:

  • Sinonasal disease was found to be ubiquitous in children with CF when assessed by coronal CT scanning.
  • Coronal CT scanning proved to be an accurate predictor of sinonasal disease and detailed sinonasal anatomy.
  • Outpatient FESS, following pediatric pulmonologist assessment, demonstrated a safe profile with lower morbidity than conventional sinus surgery.

Conclusions:

  • Coronal CT scanning is a valuable tool for diagnosing and characterizing sinonasal disease in pediatric CF patients.
  • Functional endoscopic sinus surgery is a safe and effective treatment option for sinonasal disease in children with CF, offering reduced morbidity.
  • Multidisciplinary care involving pulmonologists and surgeons is essential for optimal management of sinonasal complications in CF.

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