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Massive dedifferentiated chondrosarcoma affecting whole mandible with high recurrence potential
Niranjan Mishra1, Akhilesh Kumar Singh2, Rahul Agrawal3
1Department of Oral and Maxillofacial Surgery, Sriram Chandra Bhanja Dental College and Hospital, Cuttack, Odisha, India.
National Journal of Maxillofacial Surgery
|July 9, 2016
Summary
Chondrosarcomas are rare malignant cartilage tumors. This case highlights a massive, recurring dedifferentiated chondrosarcoma in the mandible, emphasizing the need for surgical management and follow-up.
Area of Science:
- Oncology
- Orthopedic Surgery
- Maxillofacial Surgery
Background:
- Chondrosarcomas (CS) are malignant mesenchymal tumors producing cartilage.
- Benign cartilage tumors in jaws often represent low-grade CS.
- Maxillofacial CS affects the maxilla more than the mandible, <2% of jaw tumors.
Observation:
- Clinical presentation includes swelling, pain, tooth loosening, and widened periodontal ligament.
- The case involves a 55-year-old female with massive, multiple, recurring dedifferentiated CS of the mandible.
Findings:
- Dedifferentiated chondrosarcoma is an aggressive subtype.
- Recurrence and multiplicity indicate challenging disease progression.
- Mandibular involvement presents unique surgical and functional considerations.
Implications:
- Wide surgical excision is the primary treatment for chondrosarcoma.
- Regular follow-up is crucial due to the potential for recurrence.
- This case underscores the importance of vigilant management of recurrent mandibular chondrosarcoma.

