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Virus Infection and Titration of SARS-CoV in Mouse Lung
Craig Fett1, Jincun Zhao1, Stanley Perlman1
1Microbiology Department, University of Iowa, Iowa City, USA.
Bio-Protocol
|July 9, 2016
Abstract:
Two critical steps when investigating an animal model of a virus infection are consistently successfully infecting animals and accurately determining viral titers in tissue throughout the course of infection. Here we discuss in detail how to infect mice with SARS-CoV and then quantify the titer of virus in the lung.
