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Updated: Mar 18, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
The Management of Iatrogenic Obstructive Sleep Apnoea Syndrome Following Bimaxillary Surgery in a Patient with Cleft
Giovanni Gerbino1, Fernando Carmine Gervasio, John Blythe
1*Department of Surgical Sciences, Maxillofacial Surgery Section (Head: Prof G. Ramieri)†Department of Surgical Sciences, ENT Section (Head: Prof R. Albera), San Giovanni Battista Hospital, University of Turin, Turin, Italy‡European Face Centre (Head: Prof M. Mommaerts), University Hospital of Brussels, Brussels, Laarbeeklaan, Belgium.
Abstract:
A 26-year-old man presented with a 6-year history of severe obstructive sleep apnoea syndrome followed a bimaxillary osteotomy procedure for a class III skeletal pattern. The patient was born with a unilateral cleft lip and palate and underwent primary lip and palate repair and later a pharyngeal flap for severe velopharyngeal insufficiency. Surgical management of obstructive sleep apnoea syndrome with conventional osteotomy, in cleft lip and palate patients, is a difficult problem. Distraction osteogenesis may provide a safer alternative. The authors describe and discuss the indications and the technical challenge of a multistage treatment protocol with distraction osteogenesis.
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