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Updated: Mar 18, 2026
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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Aortic Endograft and Epithelioid Sarcoma: A Random Association or Causality?
Journal of Drugs in Dermatology : JDD
|July 9, 2016
Summary
This case report details a rare instance of epithelioid angiosarcoma (EA) in a patient with a Dacron® endograft. It suggests Dacron®, a polyethylene terephthalate polymer, may be a potential carcinogen linked to this aggressive cancer.
Area of Science:
- Oncology
- Dermatology
- Vascular Surgery
Background:
- Angiosarcoma is a rare soft tissue malignancy.
- Epithelioid angiosarcoma (EA) is an aggressive subtype.
- Dacron® endografts are used for abdominal aortic aneurysm (AAA) repair.
Observation:
- A 64-year-old male presented with symptoms of fever, weight loss, and skin eruption.
- Physical examination revealed erythematous and violaceous papules and nodules.
- Biopsy confirmed epithelioid angiosarcoma with metastatic disease.
Findings:
- The patient had a history of AAA repair with a Dacron® endograft.
- Histopathological analysis and immunostaining confirmed EA.
- Metastatic angiosarcoma was identified in a bone marrow biopsy.
Implications:
- This case suggests a potential carcinogenic link between Dacron® and epithelioid angiosarcoma.
- Further research is warranted to investigate Dacron® as a carcinogen.
- This highlights the importance of considering iatrogenic factors in cancer development.
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