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Updated: Mar 18, 2026

Retinal Pathophysiological Evaluation in a Rat Model
Published on: May 6, 2022
Retinal toxicity induced by antimalarial drugs: literature review and case report
Manuel Garza-Leon1, Diana Elsa Flores-Alvarado2, Juan Manuel Muñoz-Bravo3
1Departamento de Ciencias Clínicas, División de Ciencias de la Salud, Universidad de Monterrey, Monterrey, Nuevo León, México. Address: Centro Médico Hidalgo, Avenida Hidalgo 2425 Poniente, Séptimo piso, Consultorio 706, Colonia Obispado, Monterrey, Nuevo León, México.
Abstract:
Antimalarial drugs are widely used in several countries for control of rheumatologic diseases such as systemic lupus erythematosus and rheumatoid arthritis. They are still used in Mexico because of their low cost and few secondary effects, most of which are mild and reversible. Even so, at an ophthalmological level, they could produce irreversible visual damage, which is why it is important to have ophthalmological evaluation and proper follow up. We present a clinical case as an example of characteristic ophthalmological findings as well as risk factors for retinal toxicity. We then discuss guidelines for diagnosis and follow up of patients who use antimalarial drugs for the treatment of rheumatologic illnesses.
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