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Related Concept Videos

z Scores and Unusual Values01:07

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The z score is one of the three measures of relative standing. It describes the location of a value in a dataset relative to the mean. z scores are obtained after the standardization of the values in a dataset. The z score for the mean is 0.
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z scores are the standardized values obtained after converting a normal distribution into a standard normal distribution. A z score is measured in units of the standard deviation. The z score tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a z score of...
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Spearman's rank correlation test, also known as Spearman's rho, is a nonparametric method for assessing the strength and direction of association between two variables. This test is particularly valuable when the data distribution is unknown or when the assumption of normality does not hold. Named after the English psychologist and statistician Dr. Charles Edward Spearman, it serves as the nonparametric counterpart to Pearson's correlation coefficient.
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Introduction to z Scores01:06

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A z score (or standardized value) is measured in units of the standard deviation. It tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
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Kendall's Coefficient of Concordance (W), also known as Kendall's W, is a non-parametric statistical measure used to assess the agreement or concordance between multiple raters or judges when they rank a set of items. It is often used when you have ordinal data (ranks) and you want to see if there is consistency or consensus among the raters. It is widely applied in research areas such as psychology, medicine, and social sciences, where multiple judges are asked to rank or rate subjects...
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The relation between vitamin B12 and SYNTAX score.

Levent Cerit1, Hamza Duygu, Kamil Gulsen

  • 1Near East University, Cyprus. drcerit@hotmail.com.

Kardiologia Polska
|July 9, 2016
PubMed
Summary
This summary is machine-generated.

Vitamin B12 deficiency is linked to more severe coronary artery disease. Patients with low vitamin B12 levels had higher SYNTAX scores, indicating complex blockages in heart arteries.

Keywords:
SYNTAX scorecoronary artery bypass graft surgeryvitamin B12

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Area of Science:

  • Cardiology
  • Nutritional Science
  • Biochemistry

Background:

  • Vitamin B12 is crucial for homocysteine metabolism.
  • Vitamin B12 deficiency is associated with endothelial dysfunction and cardiovascular disease through hyperhomocysteinemia.
  • The link between vitamin B12 levels and coronary artery disease severity was previously unexamined.

Purpose of the Study:

  • To investigate the association between vitamin B12 levels and the severity of coronary artery disease.
  • To evaluate the relationship between vitamin B12 and SYNTAX score in patients undergoing coronary artery bypass grafting.

Main Methods:

  • Retrospective review of medical records for 127 patients who underwent coronary artery bypass grafting.
  • Evaluation of vitamin B12 levels, other biochemical markers, clinical and echocardiographic parameters.
  • Assessment of SYNTAX score to quantify coronary artery disease complexity.

Main Results:

  • Patients with vitamin B12 deficiency exhibited a higher prevalence of cardiovascular risk factors, including diabetes mellitus, transient ischemic attack/stroke, and heart failure.
  • A significantly higher SYNTAX score was observed in patients with vitamin B12 deficiency (29.2 ± 4.9) compared to those with sufficient levels (22.5 ± 4.5, p < 0.05).

Conclusions:

  • Vitamin B12 deficiency is significantly associated with a higher SYNTAX score.
  • This finding suggests that vitamin B12 deficiency correlates with increased severity and complexity of coronary artery disease.