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[Not Available].

Amenan Geneviève N'Guessan-Irié1, Jean-Claude Yavo2, Antoine Serge Guillaume Amari3

  • 1Direction de la Pharmacie et du Médicament, Abidjan, Côte d'Ivoire; Laboratoire de Pharmacologie, de Pharmacie Clinique, de Thérapeutique et de Physiologie, UFR des Sciences Pharmaceutiques et Biologiques Université de Cocody Abidjan, Côte d'Ivoire.

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Summary
This summary is machine-generated.

Medicinal alerts in Ivory Coast from 2001-2010 reveal safety concerns, primarily from pharmaceutical companies and the French Drug Agency. This data highlights the need for a national pharmacovigilance center.

Keywords:
Côte d’IvoireIvory Coastalertesalertsarrêts de commercialisationretraits de lotsstops of marketingwithdrawals of lots

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Area of Science:

  • Pharmacovigilance and drug safety monitoring.
  • Pharmaceutical market analysis in West Africa.

Context:

  • The Directorate of Pharmaceutical and Medicinal Products (DPM) in Ivory Coast tracked medicinal alerts between 2001 and 2010.
  • Understanding drug safety trends is crucial for public health in developing nations.

Purpose:

  • To establish a more efficient system for monitoring the safety of medicines used by humans in Ivory Coast.
  • To analyze the types and sources of medicinal alerts reported over a decade.

Summary:

  • A total of 237 medicinal alerts were recorded, including 145 marketing suspensions, 55 batch withdrawals, 33 information notices, and 4 temporary suspensions.
  • Alerts originated primarily from pharmaceutical companies (49%) and the French Drug Agency (ANSM) (43%).
  • The most affected therapeutic areas were infectious diseases (22%) and pneumology (18%), with motivations including commercial reasons and unfavorable risk-benefit profiles.

Impact:

  • The findings provide a valuable database for surveying the Ivory Coast medicines market.
  • These results underscore the urgency of establishing a dedicated national pharmacovigilance center.